30 Dec 2018
Hearts can get 'younger' with physical activity
BY Tom Walker
People who take up exercise in their later years – regardless of their previous activity levels – are able to considerably improve their heart health through physical activity.
A study, published in the American Heart Association's journal, Circulation, found that two years of exercise improved maximal oxygen uptake and decreased cardiac stiffness in previously sedentary healthy middle-aged adults.
The finding suggests that regular exercise may provide protection against the risk of future heart failure.
Poor fitness in middle age is a risk factor for heart failure, particularly heart failure with a preserved ejection fraction (HFpEF).
The development of HFpEF has been linked with increased left ventricular (LV) stiffness, a consequence of sedentary ageing.
The study was based on 61 healthy, sedentary, middle-aged (aged 48-58) participants who were randomly assigned to either two years of exercise training or a control group without exercise.
The participants' LV end-diastolic pressure-volume relationships and LV stiffness – as well as calculate maximal oxygen uptake (Vo2max) – were then assessed during and after the study,
The 34 people who took part in the two-year exercise regime saw their Vo2max increase by 18 per cent, while the 27-strong control group saw their Vo2max decrease slightly.
LV stiffness in the exercise group was also reduced, whereas there was no change in the non-exercise group.
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